P4306 - How Does Inflammatory Bowel Disease Affect Hip Replacement Surgery Outcomes: Insights From the National Inpatient Sample (NIS)

Mohamed Ahmed, MD, MSc¹, Fouad Jaber, MD¹, Saqr Alsakarneh, MD¹, Islam Mohamed, MD², Ifrah Fatima, MD¹, Noor Hassan, MD³, Hassan Ghoz, MD^1
1University of Missouri - Kansas City School of Medicine, Kansas City, MO; ²University of Missouri, Kansas City, MO; ³University of Missouri Kansas City School of Medicine, Kansas City, MO

Introduction: Inflammatory bowel disease patients are at higher risk of developing hip fractures, partially due to steroids and as a sequela of extraintestinal manifestations of the disease. We examined the outcomes of hip replacement surgery in IBD patients.

Methods: Patients hospitalized between 2016 and 2020 who were admitted for Hip joint replacement were identified using International Classification of Diseases Code,10^th Revision Clinical Modification (ICD-10) identified from the Healthcare Cost and Utilization Project databases (HCUP) using the National inpatient sample (NIS). Patients who had history of IBD whether Crohn disease or ulcerative colitis were compared to patients with no IBD.

Results: A total of 2720850 hip replacement hospitalizations were identified out of which 15735 (0.57%) patients had IBD. 57.6% of patients with IBD were females as compared to 58.2% in the non IBD group. Patients with IBD were younger with mean age of 66.5 years ( 95% CI 66.1-66.9) as compared to 68.7 years ( 95% CI 68.6-68.8). The mortality rate in the IBD group was 0.7% while it was 0.41% in the non IBD group. The mean length of stay for the non IBD group is 3.03 days ( 95% CI 3-3.1) as compared to 4.1 days ( 95% CI 4.03-4.3). Total charges were similar in both groups. Patients with history of IBD were more likely to develop post operative infections ( OR 2.31, 95% CI 1.35-3.24), deep vein thrombosis ( DVT) ( OR 1.42, 95% CI 1.13-1.92) and acute kidney failure ( OR 1.76, 95% CI 1.43-1.87). Multivariate analysis showed that history of coronary artery disease, chronic kidney disease and history of colectomy are predictors of mortality in patients with IBD.

Discussion: It appears that IBD is a risk factor for patients undergoing hip replacement surgery. DVT prophylaxis should be emphasized in this cohort as IBD possesses an additional risk for DVT. Also, closer monitoring for infection is important in this population.


Disclosures:


Mohamed Ahmed, MD, MSc¹, Fouad Jaber, MD¹, Saqr Alsakarneh, MD¹, Islam Mohamed, MD², Ifrah Fatima, MD¹, Noor Hassan, MD³, Hassan Ghoz, MD¹. P4306 - How Does Inflammatory Bowel Disease Affect Hip Replacement Surgery Outcomes: Insights From the National Inpatient Sample (NIS), ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.