Government Medical College and Hospital Surat, Gujarat, India
Meetkumar V.. Pipaliya, MBBS1, Rajiv Mehta, MBBS, MD2, Dhvani Adhvaryu, PharmD2, Apoorva Doshi, MBBS3, Archi Patel, 2, Litinkumar V.. Sardhara, MBBS1, Mayank Kabrawala, DM2, Nixat Patel, MBBS1, Sankalp Parikh, MBBS, MD4 1Government Medical College and Hospital, Surat, Gujarat, India; 2Surat Institute of Digestive Sciences Hospital, Surat, Gujarat, India; 3Seth Gordhandas Sundardas Medical College and KEM Hospital, Surat, Gujarat, India; 4SIDS Hospital and Research Center, Surat, Gujarat, India
Introduction: Age continues to be a contentious element in determining the clinical course of Acute Pancreatitis. The primary goal was to study the clinical course and mortality rate of acute pancreatitis in the elderly compared to the non-elderly age group.
Methods: An ambispective data of a total of 525 patients diagnosed with Acute pancreatitis, hospitalized and followed up till discharge from year June 2017 to February 2024 were included in the study. Patients above 65 years were included in the elderly group and others in the non-elderly group. The parameters like etiology, co-morbidities, organ failure, necrosis, hospital stay, and mortality were assessed in the elderly and non-elderly populations.
Results: One hundred and seventy-five patients were included in the elderly group and 350 in the non-elderly group. Out of them, 377 were male, and 148 were female (98:77 vs 279:71; p=0.0001). Gallstone was found to be the most common cause in the elderly (74.3% vs. 32.6%; p< 0.0001), while Idiopathic pancreatitis (20% vs. 36.3%; p< 0.0013), alcohol (2.3% vs 22.8%; p< 0.0001) and hypertriglyceridemia (1.1% vs. 6.2%; p=0.0137) in non-elderly. The Charlson (42.3% vs 0.2%; p=< 0.0001) and Elixhausner (21.7% vs. 4%; p=< 0.0001) co-morbidity indices were significant in the elderly group. Necrosis (17.1% vs 33.7%; p=0.0021) was noticed more in non-elderly and Transient organ failure (22.8% vs 7.7%; p< 0.0001) in the elderly; however, persistent/progressive organ dysfunction (3.4% vs. 2.8%; p=0.2359) was similar in both age groups. There was no significant difference in hospital stay (34.3 % vs 41.7%; p=0.5401) and mortality (5.1% vs 2.8%; p=0.1864) between both age groups. Persistent organ failure (p=0.00009), necrosis (p=0.05615) and hospital stay (p=0.00037) were found to be independent predictors of mortality in the elderly.
Discussion: Biliary Pancreatitis was found to be the most common etiology in elderly population. In spite of co-morbidities being significant in elderly; ward stay, mortality and persistent organ failure were similar in both age groups.
Note: The table for this abstract can be viewed in the ePoster Gallery section of the ACG 2024 ePoster Site or in The American Journal of Gastroenterology's abstract supplement issue, both of which will be available starting October 27, 2024.
Disclosures:
Meetkumar Pipaliya indicated no relevant financial relationships.
Rajiv Mehta indicated no relevant financial relationships.
Dhvani Adhvaryu indicated no relevant financial relationships.
Apoorva Doshi indicated no relevant financial relationships.
Archi Patel indicated no relevant financial relationships.
Litinkumar Sardhara indicated no relevant financial relationships.
Mayank Kabrawala indicated no relevant financial relationships.
Nixat Patel indicated no relevant financial relationships.
Sankalp Parikh indicated no relevant financial relationships.
Meetkumar V.. Pipaliya, MBBS1, Rajiv Mehta, MBBS, MD2, Dhvani Adhvaryu, PharmD2, Apoorva Doshi, MBBS3, Archi Patel, 2, Litinkumar V.. Sardhara, MBBS1, Mayank Kabrawala, DM2, Nixat Patel, MBBS1, Sankalp Parikh, MBBS, MD4. P1723 - Characteristics and Outcomes of Acute Pancreatitis in Elderly vs Non-Elderly Patients: A Retrospective Study, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.
