P1946 - Completion of Bowel Prep at Least 8 Hours Prior to Colonoscopy Ensures an Adequate Quality of Prep

Alexander Perez, ¹, Anika Koka, ², Julian Ignacio Perez, BS³, Julian Perez-Barrios, MD^4
1University of Central Florida, Fort Myers, FL; ²Canterbury School, Fort Myers, FL; ³Stanford University, Stanford, CA; ⁴Gastroenterology Associates, Fort Myers, FL

Introduction: Quality of bowel preparation is significantly better in patients with a shorter time between bowel preparation and the start of colonoscopy.In certain group of patients, travel time to the endoscopy center plays a significant role in when they finish their prep .The aim of our study was to find the maximal time interval from bowel prep completion to colonoscopy start time which would ensure an adequate bowel preparation.

Methods: A retrospective review was conducted of 1000 adult patients who underwent a screening colonoscopy at an outpatient surgery center between March 2023 and June 2024. A split dose regimen was used for all preps.Patients were instructed to start their second dose 6 hours prior to their scheduled procedure time and finish within an hour. Time from completion of last dose of prep to colonoscopy procedure start time was recorded as C-P.Quality of prep was rated as 1 to 4 1= excellent/good,2=adequate,3=fair,4=poor.Secondary objectives included comparing prep score across age,race,gender,diabetes,BMI,Direct access colonoscopy(DAC)Statistical analysis was performed using R programming language and Bayesian information criteria to find a reduced model which best fit the data. Welch Two sample T test was performed to test the null hypothesis that the quality of prep is equal between the groups for these different variables.

Results: A total of 438 patients in DAC and 432 in nonDAC patients were identified.On analyzing the entire group, the mean time difference C-P for prep quality of 3, (fair) was 8.90 hours and prep quality 4 (poor) was 10.46 hrs
On a sub analysis of DAC patients C-P was similar, for prep score of 3 was 8.28 and prep score 4 was 8.37
There was no statistical difference between DAC and non DAC groups, or variables including age, race,gender,BMI.
Overall the time difference C-P of a bowel prep score of 1&2 is significantly lower than the bowel prep score of 3 &4.
The time difference C-P for the entire group is statistically significant with a p-value of 2.82x10^-10.

Discussion: The study provides useful insight into when the second dose of bowel prep needs to be completed to get an adequate quality preparation .A window of less than 8 hours from completion of bowel prep seems to ensure at least an adequate preparation minimizing the need of a repeat colonoscopy.This information would be helpful in subset of patients where C-P time is compromised due to multiple factors including travel times and schedule delays.



Disclosures:


Alexander Perez, ¹, Anika Koka, ², Julian Ignacio Perez, BS³, Julian Perez-Barrios, MD⁴. P1946 - Completion of Bowel Prep at Least 8 Hours Prior to Colonoscopy Ensures an Adequate Quality of Prep, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.