P2608 - High Prevalence of Atopy in Patients With Inflammatory Bowel Disease: A Retrospective Study

Alexander M. Carlson, DO¹, Ikjot Singh, MD¹, Courtney Dennis, MD², Weam Altaher, DO¹, Erin Ly, MD^1
1University at Buffalo, Buffalo, NY; ²University of Buffalo, Buffalo, NY

Introduction: Inflammatory bowel disease (IBD) often profoundly affects a patient’s quality of life. Recent studies have found a potential link between IBD and atopic conditions, suggesting a higher prevalence of atopy in patients with IBD compared to the general population. Here we present our single-center study that was aimed to explore the potential relationship between atopy and inflammatory bowel disease, in order to better understand our patient population.

Methods: At our hospital, we identified 124 patients with inflammatory bowel disease who maintained regular follow up at our gastroenterology clinic. The patient’s medical records were examined for various characteristics including number of allergies ranging from 0 to >2, gender, race and age of diagnosis. Allergies were recorded as either 0, 1, 2, or >2. Data was analyzed using simple mathematics and a Welch’s ANOVA.

Results: Out of the 124 patients examined, 48 patients (38.7%) did not report allergies. The remaining 76 (61.2%) patients reported at least 1 allergy. Of the patients with allergies, 30 patients (39.4%) had 1 listed allergy, 14 patients (18.4%) had 2 listed allergies, and 31 patients (40.7%) had 3 or more allergies (Figure 1). When employing Welch's ANOVA to examine potential associations between allergies and gender, race, or age of diagnosis, no statistically significant relationships were observed.

Discussion: In conclusion, our study reveals a strong association between atopy and IBD. Our findings, compared to a 2021 CDC study reporting a 31.8% prevalence of allergies among adults, underscore the heightened allergy burden in individuals with IBD. While further research is necessary to elucidate the underlying mechanisms and clinical implications of this, our results signify the importance of considering atopy as a potential comorbidity in the management of IBD. This understanding may inform more targeted therapeutic approaches and enhance patient care in the future.



Disclosures:


Alexander M. Carlson, DO¹, Ikjot Singh, MD¹, Courtney Dennis, MD², Weam Altaher, DO¹, Erin Ly, MD¹. P2608 - High Prevalence of Atopy in Patients With Inflammatory Bowel Disease: A Retrospective Study, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.