Shanti Patel, MD1, Ahmad Nawaz, MD2, Abdelkader Chaar, MD2, Rabia Rizwan, MD3, Dhruv Mehta, MD4, Ganesh Aswath, MD2, Hafiz Muzaffar Akbar Khan, MD2 1Yale New Haven Hospital, New Haven, CT; 2SUNY Upstate Medical University, Syracuse, NY; 3Yale New Haven Health, New Haven, CT; 4Hackensack Meridian Health, Edison, NJ
Introduction: With the increase in number of liver transplant recipients over the last decade, there are limited data available about the nationwide trends of complications leading to readmissions post-Endoscopic retrograde cholangiopancreatography (ERCP) in these patients.
Methods: Patients with a history of liver transplant undergoing ERCP from January 2018 to November 2018 were identified using International Classification of Diseases, 10, Clinical Modification (ICD-10-CM) codes from the healthcare cost and utilization project’s (HCUP) national readmission database (NRD). The common causes of unplanned 30-day readmission after ERCP procedure were determined. Multivariate logistic regression analysis was used to analyze the predictors of readmission. Discharge weights were applied to provide national estimates.
Results: During the study period in 2018, 2205 ERCPs were performed in liver transplant recipients. Of them, 200 (9.07%) had at least one unplanned readmission within 30 days. Sepsis (12.50%), enterocolitis due to C. difficile (5.39%), acute kidney failure (4.69%), angiodysplasia of stomach and duodenum with bleeding (4.11%), and anemia (3.14%) were the top 5 causes of readmissions in 30 days and accounted for almost third of all readmissions. Significant predictors of readmissions included nonalcoholic hepatic steatosis (OR 3.56; 95% CI 1.66-7.64; p=0.001) and metastatic cancer (OR 4.89; 95% CI 1.55-15.48; p=0.007).
Discussion: Unplanned readmissions in liver transplant patients undergoing ERCP remain significantly high, especially in the first 30 days post-procedure. Our study highlights the predictors of readmission and the unmet need to improve the adverse event profile in these patients.
Figure: Table 1
Note: The table for this abstract can be viewed in the ePoster Gallery section of the ACG 2024 ePoster Site or in The American Journal of Gastroenterology's abstract supplement issue, both of which will be available starting October 27, 2024.
Disclosures:
Shanti Patel indicated no relevant financial relationships.
Ahmad Nawaz indicated no relevant financial relationships.
Abdelkader Chaar indicated no relevant financial relationships.
Rabia Rizwan indicated no relevant financial relationships.
Dhruv Mehta indicated no relevant financial relationships.
Ganesh Aswath indicated no relevant financial relationships.
Hafiz Muzaffar Akbar Khan indicated no relevant financial relationships.
Shanti Patel, MD1, Ahmad Nawaz, MD2, Abdelkader Chaar, MD2, Rabia Rizwan, MD3, Dhruv Mehta, MD4, Ganesh Aswath, MD2, Hafiz Muzaffar Akbar Khan, MD2. P1050 - National Landscape of Unplanned 30-Day Readmissions in Liver Transplant Patients Undergoing ERCP: Insights from National Readmission Database, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.
