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Sunday Poster Session

Category: Biliary/Pancreas

P0049 - Role of Prophylactic Antibiotics after Endoscopic Ultrasound-Fine Needle Aspiration of Pancreatic Cysts: A Single-Center Experience

Sunday, October 27, 2024
3:30 PM – 7:00 PM ET
Location: Exhibit Hall E
Has Audio
Fjona Tabaku, MD, MPH1, Himsikhar Khataniar, MD1, Yue Yin, PhD2, Marcia Mitre, MD3, Manish K. Dhawan, MD3, Adam Kichler, DO, MS, MEd3, Gursimran S. Kochhar, MD1
1Allegheny General Hospital, Pittsburgh, PA; 2Allegheny Health Network, Pittsburgh, PA; 3Allegheny Center for Digestive Health, Pittsburgh, PA

Introduction: Antibiotics are routinely prescribed as prophylaxis after endoscopic ultrasound-fine needle aspiration of pancreatic cyst. There is a paucity of data suggesting their benefit during the procedure. In this study, our aim was to study the efficacy of using antibiotics routinely after performing endoscopic ultrasound-fine needle aspiration (EUS-FNA) of pancreatic cysts. 

Methods: A retrospective case-control study was done. All patients aged > 18 years who underwent EUS-FNA at our institution from May 2016 to June 2023 were included. Data was collected, including demographics, clinical diagnosis, antibiotic use, and complications. Complications reviewed included infections and antibiotic-related complications. Descriptive statistics were computed for demographics and primary variables. Fisher's exact test examined the association between demographics, whether or not they received antibiotics and complication rates. 

Results: A total of 205 patients were included; 117 (57.07%) were females. The mean age of participants was 65.48+/- 14.19. A total of 133 patients (64.87%) received antibiotics, while 72 (35.12%) did not. This was based on physician discretion. There were no significant differences in the complication rates among the patients who received antibiotics and those who did not (p=1). 

Discussion: The results demonstrate no significant difference in complication rates, including infections, when antibiotics are prescribed or not after performing EUS-FNA. Furthermore, antibiotic usage can result in increased healthcare costs, increased antibiotic resistance, and allergic reactions. Thus, the administration of antibiotics should be reconsidered and used on a case-by-case basis. 


Note: The table for this abstract can be viewed in the ePoster Gallery section of the ACG 2024 ePoster Site or in The American Journal of Gastroenterology's abstract supplement issue, both of which will be available starting October 27, 2024.


Disclosures:
Fjona Tabaku indicated no relevant financial relationships.
Himsikhar Khataniar indicated no relevant financial relationships.
Yue Yin indicated no relevant financial relationships.
Marcia Mitre indicated no relevant financial relationships.
Manish Dhawan indicated no relevant financial relationships.
Adam Kichler indicated no relevant financial relationships.
Gursimran Kochhar: Boston Scientific Endoscopy – Consultant. DigbI – Stock Options. Eli Lilli – Advisory Committee/Board Member, Speakers Bureau. Olympus Endoscopy – Consultant. Pentax Endoscopy – Consultant. Takeda – Consultant.


Fjona Tabaku, MD, MPH1, Himsikhar Khataniar, MD1, Yue Yin, PhD2, Marcia Mitre, MD3, Manish K. Dhawan, MD3, Adam Kichler, DO, MS, MEd3, Gursimran S. Kochhar, MD1. P0049 - Role of Prophylactic Antibiotics after Endoscopic Ultrasound-Fine Needle Aspiration of Pancreatic Cysts: A Single-Center Experience, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.