P0005 - Gender-Based Differences in Early Readmissions Following Endoscopic Drainage of Pancreatic Pseudocyst

Bhanu Siva Mohan Pinnam, MD¹, Patricia Zarza-Gulino, MD¹, Dushyant S. Dahiya, MD², Clive J. Miranda, DO, MSc³, Hema S. Pinnam, ⁴, Daksh Ahluwalia, MD¹, Abhin Sapkota, MD¹, Chun-Wei Pan, MD¹, Daniel Guifarro, MD¹, Hemant Mutneja, MD¹, Seema Gandhi, MD¹, Sumant Inamdar, MD^5
1John H. Stroger, Jr. Hospital of Cook County, Chicago, IL; ²The University of Kansas School of Medicine, Kansas City, KS; ³CHI Health Creighton University Medical Center, Omaha, NE; ⁴Jagadguru Sri Shivarathreeshwara Medical College, Mysuru, Karnataka, India; ⁵University of Arkansas for Medical Sciences, Little Rock, AR

Introduction: Pancreatic pseudocysts are a commonly encountered complication following acute pancreatitis. When symptomatic, these are often managed with endoscopic drainage. We aimed to examine gender-based differences in early readmission rates and healthcare burden.

Methods: The Nationwide Readmission Database (2016-2021) was used for this study. Using the International Classification of Disease, Tenth Revision (ICD10) codes, we identified adult patients (age > 17 years) admitted for pancreatic pseudocyst who underwent endoscopic drainage. Elective admissions and traumatic admissions were excluded. Hospitalization characteristics, 30-day readmission rates, reasons for readmission, and healthcare burden were highlighted and compared. A multivariate regression model was used to adjust for potential confounders. Kaplan-Meier survival analysis was also used to assess readmission risk.

Results: Over six years, 396 female and 523 male index admissions were identified. The mean age was 49.76 years for female and 52.98 years for male admissions (P = 0.03). Male patients had a higher 30-day readmission rate (29.8%) than female patients (19.2%) (OR 1.86, 95% CI 1.14-3.05, P = 0.012). There was no significant difference in the rates of multiple readmissions (P = 0.244). Hospitalization charges were comparable between female ($107,001) and male patients ($100,383) (P = 0.419). Female patients had longer hospital stays during readmission (7.75 days vs. 5.48 days, P = 0.036). The most commonly identified principal diagnoses on readmission were acute pancreatitis (32.82% in female and 32.69% in male readmissions) and pancreatic pseudocyst (23.22% in female and 31.18% in male readmissions). Other commonly identified principal diagnoses included sepsis (11.53% females vs. 12.51% males) and chronic pancreatitis (3.79% females vs. 5.83% males).

Discussion: Male patients faced a significantly higher risk of 30-day readmission following endoscopic drainage of pancreatic pseudocyst, despite having largely similar baseline characteristics. The most common reasons for readmission were comparable in both groups. Targeted interventions are needed to reduce overall readmission rates while tailored care is essential to mitigate such differences in adverse outcomes.



Disclosures:


Bhanu Siva Mohan Pinnam, MD¹, Patricia Zarza-Gulino, MD¹, Dushyant S. Dahiya, MD², Clive J. Miranda, DO, MSc³, Hema S. Pinnam, ⁴, Daksh Ahluwalia, MD¹, Abhin Sapkota, MD¹, Chun-Wei Pan, MD¹, Daniel Guifarro, MD¹, Hemant Mutneja, MD¹, Seema Gandhi, MD¹, Sumant Inamdar, MD⁵. P0005 - Gender-Based Differences in Early Readmissions Following Endoscopic Drainage of Pancreatic Pseudocyst, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.