P4108 - The Role of Prediabetes in Bowel Preparation Quality

Binyamin R. Abramowitz, MD¹, Su Zar Wai Hnin, MD², Helena Saba, MD², Promila Banerjee, MD, FACG³, Daniel A. DiLeo, MD⁴, Bani Chander-Roland, MD, FACG^5
1SUNY Downstate Health Sciences University, New York, NY; ²SUNY Downstate Health Sciences University, Brooklyn, NY; ³Edward Hines Jr. Veterans Affairs Hospital, Loyola University Chicago Stritch School of Medicine, Maywood, IL; ⁴Brooklyn VA Medical Center, Brooklyn, NY; ⁵VA NY Harbor Health System Clinical Associate Professor SUNY Downstate Health Sciences University, Brooklyn, NY

Introduction: Bowel preparation quality is essential for diagnostic accuracy of colonoscopy. Identifying risk factors for poor bowel preparation can help determine which patients may require an extended bowel preparation prior to their procedures. Although diabetes mellitus is a well-defined risk factor for poor bowel preparation, it is unknown as to whether prediabetes negatively influences bowel preparation. As the impact of prediabetes on bowel preparation has not been well-defined, we sought to evaluate whether prediabetes is an independent risk factor for poor quality of bowel preparation.

Methods: We performed a retrospective chart review including all patients who underwent colonoscopy at the New York Harbor Brooklyn VA Hospital Center between April and June of 2021. Patients were stratified into three groups: those with diabetes, prediabetes, and normal fasting glucose (non-diabetics). Demographic and clinical information across the three groups was collected and analyzed. A Boston Bowel Prep Score (BBPS) of 8 or 9 was considered ideal bowel preparation, while BBPS of less than 6 was considered poor bowel preparation.

Results: 245 patients were included in our study. The patient cohort consisted of 85 diabetics, 109 prediabetics, and 51 non-diabetics. There was no significant difference between the rates of ideal bowel preparation between non-diabetics and pre-diabetics (76.5% vs 72.5%, p=0.593). Pre-diabetics had a significantly higher likelihood of ideal bowel preparation than diabetics (72.5% vs 55.3%, p=0.013). There were no significant differences in rates of poor bowel preparation among the three groups of patients.

Discussion: Our data found that although prediabetic patients had significantly greater rates of ideal bowel preparation as compared to their diabetic counterparts, there was no statistically significant difference in rates of ideal bowel prep between prediabetic patients and their non-diabetic counterparts. Although prediabetes is a precursor to diabetes, our data suggests that prediabetes does not have a negative impact on bowel preparation quality. Our data also confirms the role of diabetes as a risk factor for decreased quality of bowel preparation. As our study is a relatively small, single-centered chart review, future large-scale prospective studies are needed.


Disclosures:


Binyamin R. Abramowitz, MD¹, Su Zar Wai Hnin, MD², Helena Saba, MD², Promila Banerjee, MD, FACG³, Daniel A. DiLeo, MD⁴, Bani Chander-Roland, MD, FACG⁵. P4108 - The Role of Prediabetes in Bowel Preparation Quality, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.