P3426 - Racial Disparities in Surgical Management and Outcomes In Pancreatic Adenocarcinoma: A Single Center Retrospective Study of the Last 13 Years

Dauris Rosario, MD¹, Ana Maria Davila Morales, MD², Zoë Post, MD¹, Sarah Herrera Mercedes, MD¹, Caroline Wang, MD¹, Wojciech Blogowski, MD^1
1Rush University Medical Center, Chicago, IL; ²Rush University, Chicago, IL

Introduction: Pancreatic cancer (PaC) is a significant public health challenge due to its high mortality rates, with a 5-year survival rate of 5%. Numerous investigations have examined health disparities associated with PaC, related to race and ethnicity, sex, socioeconomic status, and insurance coverage. This study aimed to assess racial disparities in the surgical management of PaC.

Methods: This retrospective single-center study included adult patients diagnosed with PaC between October 2010 and December 2023. Data collection included demographic variables as well as rates and outcomes of surgical resection in our center. Bivariate analysis was conducted using Chi-square and unpaired T-tests where applicable, with statistical significance set at a p-value of < 0.05.

Results: 529 patients diagnosed with PaC were included. Among them, 47.4% were Caucasian, 33.7% were African American, 12.6% were Hispanic, 2.1% were Asian, and 4.1% self-identified as "Other”. A total of 126 patients (23.8%) underwent a type of pancreatic resection. Despite 35% of African Americans being Stage I-II at the time of diagnosis, only 15% underwent surgical resection, a much lower rate compared to patients of both Hispanic and Caucasian ethnicity (p< 0.001). Although not statistically significant, African Americans had a lower survival time after diagnosis (399.60 days) compared to Caucasians (450.69 days) and Hispanics (427.63).

Discussion: Despite similar rates of early detection of PaC between races, African Americans tend to have lower overall rates of surgical resection compared to other ethnicities and have shorter survival times after diagnosis. Our results highlight a very significant racial disparity and the need for strategies focused on addressing barriers to care in this specific population.


Disclosures:


Dauris Rosario, MD¹, Ana Maria Davila Morales, MD², Zoë Post, MD¹, Sarah Herrera Mercedes, MD¹, Caroline Wang, MD¹, Wojciech Blogowski, MD¹. P3426 - Racial Disparities in Surgical Management and Outcomes In Pancreatic Adenocarcinoma: A Single Center Retrospective Study of the Last 13 Years, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.