P2156 - Colorectal Cancer in Focus: Trends and Insights from a National Analysis

Silpa Choday, MD¹, Sunanda Ellina, MD¹, Gautam Maddineni, MD², Indu Srinivasan, MD^3
1Creighton University School of Medicine, Phoenix, AZ; ²Florida State University, Cape Coral, FL; ³Creighton University Medical Center, Phoenix, AZ

Introduction: Colorectal cancer (CC) is the second most common cause of death in the United States. This study aims to analyze the trends in CC associated comorbidities, hospitalizations, and mortality associated with CC for over 5 years.

Methods: Nationwide Inpatient Sample (NIS) database was used to conduct a retrospective cohort study, identified CC hospitalization and investigate outcomes, including in-hospital mortality and hospital resource utilization.

Results: From 2016 to 2020, a total of 258,550 individuals were diagnosed with CC. Hospitalizations decreased from 88,745 to 80,130. The mean age of CC patients was 67.5. Males and females have similar hospitalization rates at 50% (P < 0.001). The condition was most prevalent among White individuals, though increasing trends were noted in the black population (P = 0.04). Medicare was the most common followed by private (P < 0.2). Inpatient mortality decreased from 2.9 to 2.5 (P < 0.001). The average length of stay (LOS) was 6.8 days, while total hospital charges increased from $91,851 to 97,336 (P < 0.001). Admissions to urban teaching institutions significantly rose from 64.7 to 74.3%, contrasting with a decline in rural and urban non-teaching settings (P < 0.001). Comorbidities such as smoking, heart failure (HF), obesity, hypertension (HTN), renal failure, other related cancers, and diabetes showed an increasing trend (P < 0.001). There was an increasing trend in discharges (DC) to home with home health (HH) care and decreasing DC to skilled nursing facilities (SNF), short-term facilities (P< 0.001).

Discussion: This study showed an increased trend in hospitalizations for CC. Comorbidities include smoking, HF, obesity, HTN and diabetes. Similar prevalence is observed in males and females, with increasing trends in blacks on Medicare insurance. This study highlights increasing needs for CC screening without gender disparity due to high healthcare utilization, and the overall economic burden associated with CC.



Disclosures:


Silpa Choday, MD¹, Sunanda Ellina, MD¹, Gautam Maddineni, MD², Indu Srinivasan, MD³. P2156 - Colorectal Cancer in Focus: Trends and Insights from a National Analysis, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.