P0316 - A Rare Case of MALT Lymphoma in the Colon

Serena Korkmaz, MD, Camille Boustani, MD, Srikar Reddy, MD, Chalhoub Walid, MD
MedStar Georgetown University Hospital, Washington, DC

Introduction: Mucosa-associated lymphoid tissue (MALT) lymphoma is a type of non-Hodgkin lymphoma most commonly found in the stomach. Colonic involvement is very rare with MALT lymphoma making up less than 0.5% of colon cancers. Only a few case reports have described colonic MALT lymphoma thus far.

Case Description/Methods: We describe an asymptomatic 46-year-old patient who underwent a routine screening colonoscopy that resulted in a diagnosis of MALT lymphoma. During the colonoscopy, five total polyps were found in the cecum and appendiceal orifice with histology showing low-grade B-cell lymphoproliferative disorder concerning for MALT lymphoma. A whole-body PET CT scan confirmed the lymphoma was localized to the bowel. Diagnosis with stage I MALT lymphoma was made and the patient was scheduled for surgical resection. Rituximab may be added to the treatment regimen pending surgical pathology. The treatment options are expected to be curative.

Discussion: MALT lymphoma in the colon is rare, and gastroenterologists will benefit from awareness when performing colonoscopies. Furthermore, given the rarity, these patients have no established treatment regimens although surgery with chemotherapy is widely utilized. Further reported cases in literature may aid in the diagnosis and treatment of these rare cases.


Disclosures:


Serena Korkmaz, MD, Camille Boustani, MD, Srikar Reddy, MD, Chalhoub Walid, MD. P0316 - A Rare Case of MALT Lymphoma in the Colon, ACG 2024 Annual Scientific Meeting Abstracts. Philadelphia, PA: American College of Gastroenterology.